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From the nearest airports (Falconara, Rimini and Bologna), take the train to Pesaro station and then take Line 46 bus to reach Urbino.
From Pesaro railway station, take Line 46 bus to reach Urbino.
From Bologna (175 Km): A14 toll-road, Pesaro-Urbino exit, take the SP423 road (26 Km)
From Ancona (100 Km): A14 toll-road, Fano exit, E78-SS3 highway towards Rome-Urbino, take the E78-SS73 bis to Urbino (12 Km)
From Rome (260 Km): A1-E35-E45 toll-road, take the E45-SS3 bis to Umbertide, continue along the SS3 towards Rome-Urbino, take the E78-SS73 bis to Urbino (12 Km)
Direct bus services connect:
Pesaro -> Urbino (Line 46 from Pesaro Station
Rome Tiburtina station -> Urbino (Rome-Urbino-Pesaro line)